Beta Amyloid Peptides

Product Code: QA-AB01 CAS Number: 107761-42-2 (β-Amyloid 1-42, HCl) Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA (1-42, human) Molecular Formula: C203H311N55O60S (1-42)

Overview

Beta amyloid (Aβ) peptides are proteolytic fragments derived from the amyloid precursor protein (APP) through sequential cleavage by β-secretase (BACE1) and γ-secretase. These peptides, particularly the 40- and 42-residue forms, aggregate into soluble oligomers and insoluble fibrillar plaques in the brains of Alzheimer's disease patients. QYAOBIO offers a comprehensive library of Aβ peptides spanning full-length forms, truncated fragments, modified variants, and labeled conjugates.

Key Features

• Full-length Aβ (1-40) and Aβ (1-42) with correct folding
• Over 45 fragment variants covering all regions
• Fluorescent (FAM, TAMRA) and biotin-labeled conjugates
• Mutant and modified forms (Pyr3, Gln22, Dutch mutation equivalents)
• Beta-sheet breaker peptides and reverse sequence controls

Product Specifications