Chlorotoxin
Overview
Chlorotoxin (CTX) is a 36-amino-acid peptide isolated from the venom of the deathstalker scorpion Leiurus quinquestriatus. It is a small, positively charged peptide containing eight cysteines connected by four disulfide bonds that block small-conductance chloride ion channels. CTX selectively binds to matrix metalloproteinase-2 (MMP-2) receptors on glioma cells, enabling preferential targeting of brain tumor cells over normal brain tissue.
Key Features
- HPLC-verified purity ≥95% or ≥98%
- Four native disulfide bonds (correctly folded)
- Amide and free acid forms available
- Lyophilized powder format
Product Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |