Histone Peptides
Overview
Histones are highly basic proteins rich in lysine and arginine residues that package and organize DNA into nucleosomes within eukaryotic cell nuclei. They protect DNA from damage and tangling while playing essential roles in gene regulation, DNA replication, and repair. Histone N-terminal tails are subject to extensive post-translational modifications — including acetylation, methylation, phosphorylation, and ubiquitination — that constitute the "histone code" governing chromatin structure and transcription.
Key Features
- Includes histone H3 N-terminal (1-20, 15-39, 21-44, 116-136) and H2B fragments (21-35, 21-41, 108-125)
- Biotin-labeled variants available for pull-down and detection assays
- ≥95% purity (HPLC) for reproducible epigenetics research
Product Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |