Mastoparan
Overview
Mastoparan is a 14-residue membrane-active polycationic peptide toxin originally isolated from wasp venom (Vespula lewisii). It directly activates heterotrimeric G-proteins by stimulating GDP/GTP exchange, mimicking the action of ligand-bound G-protein-coupled receptors. Mastoparan and its analogs are widely used as pharmacological tools for studying G-protein signaling and membrane-peptide interactions.
Key Features
- Wasp venom-derived peptide toxin
- Direct G-protein activator (GDP/GTP exchange)
- Multiple structural analogs for SAR studies
Product Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |