MCD Peptides (Mast Cell Degranulating)
Overview
Mast Cell Degranulating (MCD) peptide is a bioactive peptide isolated from bee venom with dual functionality: at low concentrations, it triggers mast cell degranulation and histamine release, while at higher concentrations it acts as a neurotoxin that selectively blocks voltage-gated potassium channels. This dual activity makes MCD peptides valuable tools for studying both inflammatory responses and ion channel physiology.
Key Features
- Dual-function peptide: mast cell degranulator and voltage-gated potassium channel blocker
- Available as MCD Peptide HR-1 (INLKAIAALVKKVL-NH₂, CAS 80533-94-4) and the full-length disulfide-bridged MCD peptide (CAS 32908-73-9)
- Custom synthesis with ≥95% purity, verified by HPLC
Product Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |