Nesfatin
Overview
Nesfatin-1 is a neuropeptide derived from the precursor protein nucleobindin-2 (NUCB2), secreted by peripheral tissues and the central and peripheral nervous systems. It plays a critical role in the regulation of energy homeostasis, influencing food intake, water consumption, hunger sensation, and fat storage. Nesfatin-1 is an anorexigenic peptide that suppresses feeding independently of leptin signaling and can cross the blood-brain barrier bidirectionally.
Key Features
- 82-amino-acid peptide available in human, mouse, and rat sequences
- Leptin-independent anorexigenic peptide that enhances insulin secretion from pancreatic β-islet cells
- Custom synthesis with ≥95% purity, verified by HPLC and LC-MS
Product Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |
| Purity | ≥95% or ≥98% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20°C, desiccated, protected from light |
| Research Use Only | Yes |